possible yes
sensible, they will be hard to remove if necessary in the future
as smidey said predrill the frame and screw on
i have had mdf properly sealed and painted that has lasted over 7 years on tank stands
if it makes you feel better i recently lost 11 tropical marines to heavy metal poisoning
some i had had for 3 years
taken 3 weeks but starting to play with the tank again but still hurts each time i look at it
the fish bug doesn't leave you for long
maybe do a water change it will come right
i find scats can start getting a bit agressive with each other and a cloudy eye can be the result
it usually comes right by itself but i do a waterchange to make sure