Hi, I don't post much, but don't please treat what you read with some scepticism sometimes...
quote: "Prazi is probably the best choice here because it’s safe for adults and young and definitely kills the flukes by rupturing the outer membrane (skin) causing then to be totally destroyed. The hooks they hold on with aren’t destroyed and will fall or decompose out on there [sic] own. "
Praziquantel acts on the calcium channels in the parasites. It results in paralysis of the parasite, which in many cases, unless the fish has encapsulated the parasite in an exuberrant epithelial response on the gills, means that the haptors (hooks) that it uses to hold on relax and the parasite falls off. In terrestrial animals prazi causes gut parasites to fall asleep, and when they wake up the animal is no longer there :-). (i.e. they are in the poo!)
Prazi does not cause the parasite to explode or disintegrate...in fact in aquaculture one problem with prazi is that at low doses the flukes can wake up again after the fish have been treated.
Anyway, the statement after that about eggs not being affected is actually true and so repeated doses are indeed needed.
Great to see peoples' experience being shared, but lets get the facts right.