Hello livingart,
Agreed that temp. and DO play a role in water quality but normally they should be fairly stable in an established system like mine for example,
14 degree, and above 6.5 mg/l O2. Which is good enough to grow demanding species like trout, that does not cover it quite well enough for me.
There must be something else going on, with still plenty of options like the nutrition in the food is not good enough, stress with too many animals, not enough hiding spots, injuries, not enough Ca2+ available from the water, infections (bacterial, virus, fungus), etc. Would like to get in contact with somebody who has a koura farm but I do not know anybody here up North, they should have come across problems like that and might have an answer.
Just keep going and try to find out more about it step by step.
Cheers
Daniel